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4-Hydroxy-α-methyltryptamine (4-HO-aMT) is a tryptamine-based psychedelic. It has comparable properties to α-methyltryptamine (αMT) but worse adverse effects like 5-MeO-aMT. TiHKAL author Alexander Shulgin briefly outlines 4-HO-αMT.

Humans were tested for 4-hydroxy αMT. Visual consequences include disorientation and depression. However, oral dosages of 15 to 20 mg caused stomach discomfort, tachycardia, elevated blood pressure, headache, and diarrhoea in some patients.

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Few animal and human research have examined this chemical. Thus, product information has been scarce. Thus, long-term consequences, dependence, toxicology, and contraindications are unknown.

4-ho-amt is less psychologically intensive but extremely visual than LSD, psilocin, and 4-AcO-DMT. The drug’s recreational and clearheaded qualities are exaggerated. Some users have powerful mental effects at normal amounts, while many may experience intense effects at high doses. 4-ho-amt, like most psychedelics, should be respected and avoided. Proper configuration and setup reduce hazards and boost therapeutic benefits.

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